| 摘要 |
NEW MATERIAL:The compound of formula I (R1 is H, i-propyl, n-butyl, n-hexyl or benzyl; R2 is H, methyl, n-butyl or benzyl). EXAMPLE:The compound of formula II. USE:An antitumor agent having strong antitumor activity. PREPARATION:A bicyclic compound of formula III (R3 is H, methyl or benzyl) is made to react with an alkyl halide such as isopropyl iodide e.g., in the presence of potassium carbonate at room temperature for 18hr under stirring. |
