发明名称 Thiophene carboxamide deriv. prepn.
摘要 The derivs. of formula (I), in which R1 is 1-4C alkylthio, alkylsulphinyl or alkylsulphonyl; R2 is 1-4C alkyl; R3 is 1-4C alkyl or 2-4C alkenyl; X is (CH2)nR4R4, R4 is 1-4C alkyl, 2-4C alkenyl or opt. substd. benzyl, and n is 1, 2 or 3. - Cpds. are made by reaction between a thiophene cpd. of formula (II), in which Z is halogen, OH or OR and R is an active gp., and an amine of formula X-NH2.
申请公布号 ES2008635(A6) 申请公布日期 1989.07.16
申请号 ES19880003049 申请日期 1988.10.06
申请人 LILLY, S.A.;LILLY INDUSTRIES LIMITED 发明人 FERNANDEZ FERNANDEZ M. ISABEL;HOTTEN TERRENCE M.
分类号 A61K31/38;C07D333/38;(IPC1-7):C07D333/38 主分类号 A61K31/38
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