摘要 |
Aminoaryl beta -sulfatoethyl sulfone compounds, such as, for example 4-( beta -sulfatoethylsulfonyl)-aniline, can be prepared in a quick and easy manner from their corresponding beta -hydroxyethyl sulfone compounds by sulfation by spraying a solution or suspension or paste of this aminoaryl beta -hydroxyethyl sulfone compound or the acylamino compound thereof in sulfuric acid or aqueous sulfuric acid into a hot inert gas stream of a convection dryer. In this procedure, the drying, esterification reaction and the hydrolysis of any acylamino group present takes place synchronously. The sulfato compound is preferably obtained in the form of granules. |