发明名称 |
Concentrated stabilized microbubble-type ultrasonic imaging agent |
摘要 |
A microbubble-type ultrasonic imaging agent is provided comprising a parenterally-administerable aqueous medium containing a dispersion of microspheres predominantly of diameters less than 10 microns, wherein the microspheres consist of gas microbubbles encapsulated with water-insolubilized biocompatible material. The imaging agent is characterized by having a concentration of greater than 100x106 microspheres per milliliter, and a stability such that this concentration is maintained for over 4 weeks at a temperature of 20 DEG to 25 DEG C.
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申请公布号 |
US4844882(A) |
申请公布日期 |
1989.07.04 |
申请号 |
US19870139576 |
申请日期 |
1987.12.29 |
申请人 |
MOLECULAR BIOSYSTEMS, INC. |
发明人 |
WIDDER, KENNETH J.;WESTKAEMPER, PETER J. |
分类号 |
A61K49/00;A61B8/00;A61K9/50;A61K49/22 |
主分类号 |
A61K49/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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