MEDICINE AND OR COMSMETICS COMPOSITION FOR LOCAL ADAPTATION

摘要

PURPOSE: To obtain a medicinal or cosmetic composition for local applicaion, combinedly containing benzoyl peroxide and a specific quaternary ammonium lipophilic salicylate on a support and useful for treating acne. CONSTITUTION: This medicinal or cosmetic composition is obtained by combinedly including benzoyl peroxide and at least one kind of a quaternary ammonium hydrophilic salicylate containing a compound of formula I R1 to R4 are each a 1-18C saturated alkyl, etc., containing one or more hydroxyl groups in terminal chains or a chain; R5 is a group of formula II [(n) is 0-16]} onto a physiologically permissible support. The quaternary ammonium lipophilic salicylate is e.g. hexadecyltrimethyl ammonium 5-octanoylsalicylate.