摘要 |
A method for mechanical processing of a plastic or elastic pharmaceutical or confectionery sample for the release of substances from said sample into a surrounding liquid medium, comprises immersing a reinforcing member into said medium, immersing said sample into said medium and subjected said sample and said member essentially simultaneously to repeated compression and shearing forces. An apparatus for carrying out said method comprises a substantially vertical container (1) releasably mounted on a base (2) and a first jaw (7) for receiving said sample (17) fixed on said base (2) and arranged in the lower end of said container (1). The lower end of said container (1) is sealed against leakage of said liquid medium. A second jaw (15) faces said first jaw (7) and is vertically movable and rotatable for subjecting said sample (17) to compression and shearing forces. The apparatus further comprises drive means (14, 16) for said second jaw (15) and a separate member (18) for reinforcing the sample (17). |