发明名称 |
PROCESS FOR PRODUCTION OF DERIVATIVES OF SUBSTITUATED INDOLINON |
摘要 |
A process which comprises reductive cyclisation of a compound of structure (II) <CHEM> in which n is 1 to 3 and X is a group displaceable by amine in the presence of at least two equivalents of anhydrous iron (III) chloride and at least two equivalents of an acetyl halide and a solvent to form a compound of structure (III) <CHEM> in which X and n are as hereinabove defined, Z is halogen. f |
申请公布号 |
HUT48583(A) |
申请公布日期 |
1989.06.28 |
申请号 |
HU19880003123 |
申请日期 |
1988.06.17 |
申请人 |
SMITH KLINE AND FRENCH LABORATORIES LTD,GB |
发明人 |
FORTUNAK,JOSEPH M.,US |
分类号 |
A61K31/40;C07C45/60;C07C45/85;C07C47/55;C07C67/00;C07C201/00;C07C205/00;C07C205/09;C07D209/34 |
主分类号 |
A61K31/40 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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