发明名称 PROCESS FOR PRODUCTION OF DERIVATIVES OF SUBSTITUATED INDOLINON
摘要 A process which comprises reductive cyclisation of a compound of structure (II) <CHEM> in which n is 1 to 3 and X is a group displaceable by amine in the presence of at least two equivalents of anhydrous iron (III) chloride and at least two equivalents of an acetyl halide and a solvent to form a compound of structure (III) <CHEM> in which X and n are as hereinabove defined, Z is halogen. f
申请公布号 HUT48583(A) 申请公布日期 1989.06.28
申请号 HU19880003123 申请日期 1988.06.17
申请人 SMITH KLINE AND FRENCH LABORATORIES LTD,GB 发明人 FORTUNAK,JOSEPH M.,US
分类号 A61K31/40;C07C45/60;C07C45/85;C07C47/55;C07C67/00;C07C201/00;C07C205/00;C07C205/09;C07D209/34 主分类号 A61K31/40
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