发明名称 |
Combined electrophoretic-separation and electrospray method and system |
摘要 |
A system and method for analyzing molecular constituents of a composition sample includes: forming a solution of the sample, separating the solution by capillary zone electrophoresis into an eluent of constituents longitudinally separated according to their relative electrophoretic mobilities, electrospraying the eluent to form a charged spray in which the molecular constituents have a temporal distribution; and detecting or collecting the separated constituents in accordance with the temporal distribution in the spray. A first high-voltage (e.g., 5-100 KVDC) is applied to the solution. The spray is charged by applying a second high voltage (e.g., +/-2-8 KVDC) between the eluent at the capillary exit and a cathode spaced in front of the exit. A complete electrical circuit is formed by a conductor which directly contacts the eluent at the capillary exit.
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申请公布号 |
US4842701(A) |
申请公布日期 |
1989.06.27 |
申请号 |
US19870034875 |
申请日期 |
1987.04.06 |
申请人 |
BATTELLE MEMORIAL INSTITUTE |
发明人 |
SMITH, RICHARD D.;OLIVARES, JOSE A. |
分类号 |
G01N27/447;H01J49/04;H01J49/16 |
主分类号 |
G01N27/447 |
代理机构 |
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主权项 |
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地址 |
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