GASTRINE FREE PEPTIDE ANTAGNIST

摘要

Small cell lung carcinoma cells (SCLC) contain gastrin releasing peptide (GRP) receptors, of the formulas: The response of the cells to GRP is rapid growth. We have found a group of heptapeptides that act as GRP antagonists by blocking the binding of GRP to its receptor thereby inhibiting the growth of cells that are sensitive to the growth promoting activity of GRP.