VACCINE COMPRISING CHARACTERISTIC EPITOPE INTEGRATED IN PICORNAVIRUS, PARTICULARLY POLIOVIRUS

摘要

The invention relates to an active principle of a vaccine whose characteristic epitope is incorporated in the capsid of a picoravirus, in particular, the poliovirus, which serves as the vector. This active principle consists of a viable picornavirus hybrid containing an epitope which is characteristic of a vaccinating protein and is heterologous in respect of the proteins of said picornavirus, instead of one of its own immunogenic epitopes.