发明名称 |
FREMGANGSMAATE FOR FREMSTILLING AV POLYETERANTIBIOTIKA VEDFERMENTERING AV STREPTOMYCES X-14889 NRRL 15517. |
摘要 |
There are presented antibiotic compounds designated as Antibiotics X-14889 A, C and D of the formulas …<CHEM>… wherein (for X-14889A) R1 is methyl, R2 is methyl, R3 is hydrogen, R4 is methyl and R5 is hydrogen or (for X-14889C) R1 is hydrogen, R2 is methyl, R3 is hydrogen, R4 is methyl and R5 is CO2H. …<CHEM>… (X-14889 D) and the pharmaceutically acceptable salts thereof. …<??>The compounds exhibit antimicrobial activity and one of the compounds X-14889C also exhibits activity against Treponema hyodysenteriae (in vitro). Plasmodium berghei and as food efficiency enhancers in ruminants. …<??>Also presented is a process to produce the above compounds and another known component Antibiotic X-14889B. |
申请公布号 |
NO160859(C) |
申请公布日期 |
1989.06.07 |
申请号 |
NO19840004663 |
申请日期 |
1984.11.22 |
申请人 |
HOFFMANN-LA ROCHE & CO. AKTIENGESELLSCHAFT, F. |
发明人 |
LIU, CHAO-MIN;WESTLEY, JOHN |
分类号 |
C07D493/08;A23K20/195;A61K31/35;A61K31/357;A61P1/12;A61P31/04;C07D317/00;C07D407/14;C12P17/06;C12P17/16;C12P19/44;C12R1/465 |
主分类号 |
C07D493/08 |
代理机构 |
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地址 |
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