| 发明名称 |
Resolved amino pyrrolidine neuroprotective agents. |
| 摘要 |
<p>The present invention provides R(+)-3-amino-1-hydroxypyrrolidin-2-one of formula I: <CHEM> or a pharmaceutically acceptable acid addition salt thereof, which compound is useful as an anticonvulsant agent and in the treatment and/or prevention of neurodegenerative disorders.</p> |
| 申请公布号 |
EP0318091(A2) |
申请公布日期 |
1989.05.31 |
| 申请号 |
EP19880202602 |
申请日期 |
1988.11.18 |
| 申请人 |
MERCK SHARP & DOHME LTD. |
发明人 |
LEESON, PAUL D.;WILLIAMS, BRIAN J. |
| 分类号 |
A61K31/40;A61P9/10;A61P25/08;A61P25/18;A61P43/00;C07C323/47;C07C323/60;C07D207/46 |
主分类号 |
A61K31/40 |
| 代理机构 |
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代理人 |
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| 主权项 |
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| 地址 |
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