Sebosuppressive compositions and method for suppressing sebaceous gland activity

摘要

Sebosuppressive compositions comprising a cosmetically- and pharmaceutically-acceptable carrier and an antiseborrheic agent consisting essentially of a 4-alkoxy- or 4-(4-alkylbenzyloxy)-benzoic acid and a purine compound corresponding to the formula: (II) or the purine 1,3,7,9-tetramethyluric acid; or a physiologically-acceptable salt thereof. The antiseborrheic action of the 4-alkoxy- or 4-(4-alkylbenzyloxy)-benzoic acids is potentiated by the purine compounds. Preferred purine compounds are theophylline, theobromine and caffeine.