| 摘要 |
PURPOSE:To provide a filler which is made of materials all replaceable with a new bone and not easily dissolved even if in contact with a place where blood is well circulated: e.g., gum, by covering a face of a porous sintered body which makes contact with a muscular tissue with a hardly-soluble member. CONSTITUTION:A porous sintered body 3 made of beta-tricalcium phosphate (beta-TCP) has a strong affinity for a bone tissue 1 and is well absorbed in the tissue 1. This advantage, i.e., high solubility of beta-TCP, is, however, a disadvantage at the same time since beta-TCP starts dissolving when it makes contact with blood in gum 2. A filler of the invention is a double-layered body consisting of the porous sintered body 3 and a sparingly-soluble member 6. The sintered body 3 is dissolved and absorbed in an organism and is replaced with a new bone soon. But the member 6, which makes contact with a place where blood is circulated, e.g., muscle, is a hardly-soluble dense body made of beta-TCP and hydroxyapatite, thus preventing the porous sintered body 3 from dissolving before a new bone is generated. |
