| 摘要 |
<p>Imidazo¢1,2-a!pyridine derivatives of the general formula: wherein Y represents a hydrogen or halogen atom or a C1-4 alkyl radical, Z represents a furan-2-yl, thien-2-yl or pyridin-2-yl radical optionally carrying a halogen atom or a methyl or ethyl radical in the 5-position, and R represents the hydroxy radical, a C1-4 alkoxy radical or a group -NRlR2 in which R1 and R2 independently of one another each represent a hydrogen atom, a straightor branched-chain C1-5 alkyl radical,optionally carrying one or more halogen atoms or a hydroxy radical, a group -N(C1-4 alkyl)2, a carbamoyl radical or a C1-4 alkoxy radical; the allyl radical, the propargyl radical; a C3-6 cycloalkyl radical, the benzyl radical; or the phenyl radical, or alternatively-NRlR2 together represent a heterocyclic ring containing from 3 to 6 carbon atoms, or a heterocyclic ring of the formula in which X is 0, S, CHOR' or N-R", R' being a hydrogen atom or the benzyl radical and R" being a hydrogen atom, a C1-4 alkyl radical or the phenyl radical optionally carrying a methoxy radical or a halogen atom, are new compounds. They are therapeutically useful as they possess anxiolytic, antianoxic, sleep-inducing, hypnotic and anticonvulsant properties.</p> |
