| 摘要 |
<p>The method of this invention yields a two phase liquid aqueous system which replicates the two phase heterogeneous physicochemical system of naturally occurring whole human blood. The method produces a composition of matter which comprises a whole blood substitute when polymerized hemoglobin ox pyridoxylatedpolymerized hemoglobin, and preferably, other specific additives are incorporated. When said blood substitute is processed further, a microencapsulated composition with time release characteristics that can transport oxygen is produced. The invention overcomes the obstacles that have prevented the use of modified hemoglobins like pyridoxylated-polymerized hemoglobin in the preparation of oxygen transport systems.</p> |
