发明名称 |
Stabilization of enteric coated dosage form. |
摘要 |
<p>The present invention is a stabilized enteric-coated pharmaceutical dosage form and processes for the preparation thereof. Dissolution stability after storage of the dosage form under high stress conditions is improved by an enteric-coated dosage form having an enteric coating wherein the coating is of the acrylic resin kind of from 14 mg/cm<2> to 24 mg/cm<2> or an enteric coating wherein the coating is of the acetate kind of from 14 mg/cm<2> to 24 mg/cm<2> and having a second coating of hydrophilic coating for example, hydroxypropyl cellulose, hydroxymethyl celluose or hydroxypropylmethyl cellulose.</p> |
申请公布号 |
EP0313845(A1) |
申请公布日期 |
1989.05.03 |
申请号 |
EP19880116035 |
申请日期 |
1988.09.28 |
申请人 |
WARNER-LAMBERT COMPANY |
发明人 |
FAWZI, MAHDI BAKIR;KUBERT, DANIEL AARON;MURTHY, KUCHI SURY |
分类号 |
A61K9/00;A61K9/32;A61K9/36;A61K9/48;A61K47/00;A61K47/38 |
主分类号 |
A61K9/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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