| 摘要 |
PCT No. PCT/US86/00780 Sec. 371 Date Dec. 15, 1986 Sec. 102(e) Date Dec. 15, 1986 PCT Filed Apr. 17, 1986 PCT Pub. No. WO86/06275 PCT Pub. Date Nov. 6, 1986.Stable retinol compositions are disclosed. The compositions comprise retinol, a volatile silicone and a mutual solvent for the retinol and silicone. Preferred compositions contain retinol, cyclomethicone and ethanol. Were the retinol level in the compositions is between 0.005 and 1.0 weight percent, the compositions may be topically applied to the skin in areas where fine lines, wrinkles or other signs of aging exist. Such topical application results in a reduction in wrinkles and fine lines and improves skin quality. Where the compositions contain more than 0.005 to 1.0 weight percent retinol they may be diluted with cosmetically acceptable carriers or vehicles, preferably water in oil emulsions to reduce the retinol level and topically applied.
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