| 摘要 |
<p>NEW MATERIAL:A compound expressed by formula I (R1 is alkyl, alkenyl, alkynyl, cycloalkyl, cycloalkylalkyl or phenoxyalkyl; R2 is H, lower alkyl or aralkyl; R3 is H or protecting group; A is ethylene or vinylene; broken lines indicate alpha- or beta-configuration or a mixture thereof) or salt thereof. EXAMPLE:Methyl [2-hydroxy-1-(3-hydroxy-5-methyl-1-nonenyl)-2,3,3a,9a-tetrahy dro-1H-cyclopenta[b][1,4]benzodioxin-5-yl]oxyacetate. USE:An antiulcer agent and antithrombotic agent. PREPARATION:For example, an aldehyde expressed by formula II (R2 is lower alkyl; R3 is protecting group) is additively reacted with a Grignard reagent to afford the corresponding compound expressed by formula I.</p> |
