| 发明名称 |
RECOMBINANT ANTIBODY AND METHOD |
| 摘要 |
PCT No. PCT/GB88/00729 Sec. 371 Date Jul. 3, 1989 Sec. 102(e) Date Jul. 3, 1989 PCT Filed Sep. 5, 1988 PCT Pub. No. WO89/01782 PCT Pub. Date Mar. 9, 1989.The present invention provides an altered antibody molecule wherein a residue in a surface pocket on the molecule has been changed to a cysteine residue to introduce a thiol group in the surface pocket and a process for its production by recombinant DNA technology. |
| 申请公布号 |
WO8901783(A3) |
申请公布日期 |
1989.04.20 |
| 申请号 |
WO1988GB00731 |
申请日期 |
1988.09.05 |
| 申请人 |
CELLTECH LIMITED |
发明人 |
BODMER, MARK, WILLIAM;ADAIR, JOHN, ROBERT;WHITTLE, NIGEL, RICHARD |
| 分类号 |
G01N33/531;A61K39/395;C07K1/22;C07K14/00;C07K16/00;C07K16/18;C07K16/30;C07K19/00;C12N5/10;C12N15/00;C12N15/09;C12N15/13;C12N15/20;C12P21/00;C12P21/02;C12P21/08;C12R1/91;G01N33/574;G01N33/577 |
主分类号 |
G01N33/531 |
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