| 发明名称 |
STABILIZED IMMUNE MODULATORY RNA (SIMRA) COMPOUNDS FOR TLR7 AND TLR8 |
| 摘要 |
The invention relates to the therapeutic use of stabilized oligoribonucleotides as immune modulatory agents for immune therapy applications. Specifically, the invention provides RNA based oligoribonucleotides with improved nuclease and RNase stability and that have immune modulatory activity through TLR7 and/or TLR8. |
| 申请公布号 |
KR20090029187(A) |
申请公布日期 |
2009.03.20 |
| 申请号 |
KR20087027357 |
申请日期 |
2007.04.06 |
| 申请人 |
IDERA PHARMACEUTICALS, INC. |
发明人 |
KANDIMALLA EKAMBAR R.;LAN TAO;LI YUKUI;YU DONG;WANG DAQING;PUTTA MALLIKARJUNA REDDY;AGRAWAL SUDHIR |
| 分类号 |
A61K31/7084;A61K31/7088;A61P37/02;C12N15/117 |
主分类号 |
A61K31/7084 |
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