| 摘要 |
PURPOSE:In the reaction between isobutylene and water and/or t-butanol and prussic acid, to obtain the titled compound in high yield, by specifying molar ratios of an acid as a catalyst and prussic acid to isobutylene and/or t-butanol. CONSTITUTION:In the preparation of N-t-butylformamide by reacting isobutylene and water and/or t-butanol with prussic acid in the presence of an acid catalyst (e.g., sulfuric acid), the reaction is carried out under conditions where a molar ratio of the acid to isobutylene and/or t-butanol is 0.05-0.8 and a molar ratio of prussic acid to isobutylene and/or t-butanol is 1.5-10, at 50-120 deg.C, preferably 60-90 deg.C. When the amount of prussic acid used is smaller than the range, side reactions such as isobutylene polymerization, etc. increase. When the reaction temperature exceeds 120 deg.C, the prepared desired compound is decomposed, the acid catalyst is poisoned by the decomposition product, and the yield of the desired compound is reduced. |
