发明名称 |
Sensor for measurement of a chemical species susceptible to dehydrogenation. |
摘要 |
<p>An electrode is provided for a single-use sensing device in a clinical chemical analyzer for amperometrically determining the level, in a body fluid, of a chemical species susceptible to dehydrogenation in the presence of a dehydrogenase enzyme. The electrode has a coating comprising the dehydrogenase enzyme, a perfluorosulfonic acid polymer, methylene blue and a cofactor of the group consisting of NAD<+> and NADP<+>. In a preferred embodiment, the coating also includes a water soluble resinous polymer and a cured aqueous emulsion adhesive. In another embodiment, the sensor is used to measure a hydrogenatable chemical species, in which case the cofactor is in hydrogenated form. In still another embodiment, the sensor is used to measure a dehydrogenase enzyme, in which case the enzyme is omitted from the coating and a dehydrogenatable chemical species is substituted therefor.</p> |
申请公布号 |
EP0311377(A2) |
申请公布日期 |
1989.04.12 |
申请号 |
EP19880309282 |
申请日期 |
1988.10.05 |
申请人 |
ARDEN MEDICAL SYSTEMS, INC. |
发明人 |
ANDERSON, CARTER;SOGIN, DAVID C.;FOWLER, WILLIAM V. |
分类号 |
G01N27/327;A61B5/00;A61B5/145;A61B5/1473;C12Q1/00;C12Q1/32;G01N27/28;G01N27/333;G01N27/416 |
主分类号 |
G01N27/327 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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