发明名称 Quinoline intermediates for the synthesis of 1H-imidazo[4,5-c]quinolines and 1H-imidazo[4,5-c]quinolin-4-amimes.
摘要 <p>Compounds of the types (I) and (II) are disclosed, &lt;CHEM&gt; wherein each R5 is independently selected from the group consisting of alkyl of one to about four carbon atoms, alkoxy of one to about four carbon atoms and halogen, and n is an integer from 0 to 2, with the proviso that if n is 2, then said R5 substituents together contain no more than 6 carbon atoms; R6 is selected from the group consisting of hydroxyalkyl of one to about six carbon atoms and cyclohexylmethyl; and R7 is selected from the group consisting of alkyl of one to about four carbon atoms and hydrogen. These compounds may be used as intermediates for the synthesis of 1H-imidazo[4,5-c]quinoline derivatives.</p>
申请公布号 EP0310950(A1) 申请公布日期 1989.04.12
申请号 EP19880116137 申请日期 1984.11.16
申请人 RIKER LABORATORIES, INC. 发明人 GERSTER, JOHN F.
分类号 C07D471/04;A61K31/435;A61K31/47;A61P11/08;A61P31/12;C07D;C07D215/42;G06F5/01;G06K15/12;(IPC1-7):C07D215/42 主分类号 C07D471/04
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