发明名称 |
Multidentate chelators based on the 8-hydroxyquinoline unit. |
摘要 |
<p>The present invention provides linear, cyclic and trifurcate tri- and tetramine backbone multidentate chelating agents based on the 8-hydroxyquinoline chelating unit. The chelating agents may optionally be substituted with a substrate reactive moiety and antibody-metal ion conjugates may be produced for in vivo diagnostic and therapeutic methods.</p> |
申请公布号 |
EP0308757(A1) |
申请公布日期 |
1989.03.29 |
申请号 |
EP19880114864 |
申请日期 |
1988.09.12 |
申请人 |
ABBOTT LABORATORIES |
发明人 |
JOHNSON, DAVID K.;KLINE, STEVEN J. |
分类号 |
C07D215/26;A61K51/04;A61K51/10;C07C67/00;C07C209/00;C07C211/29;C07C213/00;C07C215/48;C07C215/76;C07C239/00;C07C259/06;C07C271/20;C07C271/22;C07D213/56;C07D213/65;C07D215/48;C07D401/14;C07K1/113;C07K7/04;C07K14/00;C07K14/705;C07K14/745;C07K16/00;C09K3/00;(IPC1-7):C07D215/48;A61K49/02;C07C87/28 |
主分类号 |
C07D215/26 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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