发明名称 |
Method of inactivating reproductive filterable pathogens in fibrinogen and factor XIII compositions |
摘要 |
There is disclosed a method of inactivating reproductive filterable pathogens in tissue adhesives containing fibrinogen and Factor XIII, with their biologic activity being largely preserved. In order to provide a tissue adhesive preparation of human or animal origin, which exhibits a high safety with respect to reproductive filterable pathogens and whose biologic activity is largely preserved, preparations having a minimum content of 100 units of Factor XIII/g of fibrinogen are heated in the dry state in the presence of an oxygen-free inert protective gas or under vacuum.
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申请公布号 |
US4816251(A) |
申请公布日期 |
1989.03.28 |
申请号 |
US19850775609 |
申请日期 |
1985.09.13 |
申请人 |
IMMUNO AKTIENGESELLSCHAFT FUR CHEMISCH-MEDIZINISCHE PRODUKTE |
发明人 |
SEELICH, THOMAS |
分类号 |
A61K35/14;A61K35/16;A61K38/16;A61K38/43;A61L2/00;A61L2/04;(IPC1-7):A61K35/14 |
主分类号 |
A61K35/14 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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