| 摘要 |
A solid phase N-hydroxysuccinimide reagent having the general formula: <IMAGE> where X is particulate silica gel or controlled pore glass; n=3-7; Y is either (CH2)n' or (CH2)n'-NH-CO-CH2 wherein n'=2-6; Z may be in the form of OCOR, OSO2R and OCO2R, and Z' may be either Z or OH, wherein R is a chromophore, fluorophore or electrophore capable of detection in chromatographic separation technology is disclosed. Also disclosed is the method for making compounds of this type and the method for using these compounds to identify and quantitate analytes having primary or secondary amine or thiol functionalities.
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