PROCEDE D'OBTENTION PAR VOIE CHIMIQUE D'OLIGONUCLEOTIDES MARQUES ET APPLICATIONS BIOLOGIQUES

摘要

The process described is characterized in that activated thymidines are incorporated in the 4 position, in the place of cytidines, in an oligonucleotide sequence during construction, the sequence formed is reacted with a bifunctional compound, and a marker is attached to the function which remains free.