发明名称 Crystalline L-carnosine zinc complex and production thereof.
摘要 <p>A novel crystalline L-carnosine zinc complex is produced by reacting L-carnosine, a zinc salt and an alkali metal compound in an anhydrous or hydrous polar organic solvent. The crystalline L-carnosine zinc complex substantially corresponds to the formula C9H12N4O3Zn and has physical properties clearly different from the known amorphous L-carnosine zinc complex. As compared with the amorphous complex, the crystalline complex is very low in impurity, stable to heat and moisture, and easy to filtrate, and has higher antiulcer activity.</p>
申请公布号 EP0303380(A2) 申请公布日期 1989.02.15
申请号 EP19880307090 申请日期 1988.08.01
申请人 HAMARI YAKUHIN KOGYO KABUSHIKI KAISHA ALSO KNOWN AS HAMARI CHEMICALS LTD. 发明人 MATSUKURA, TAKEFUMI;TAKAHASHI, TAMIKO;NISHIMURA, YASUHIRO;TAKAYA, MASAHIRO;FUJIMURA, HAJIME
分类号 C07D233/64;A61K31/415;A61K38/00;A61P1/04;C07D233/54;C07F3/00 主分类号 C07D233/64
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