发明名称 |
OMEGA-CYCLOALKYL PROSTAGLANDINS |
摘要 |
This invention encompasses prostaglandins of the formula I <IMAGE> I wherein R''' represents hydroxymethyl, hydroxyacetyl or -CO2R'''' wherein R'''' represents hydrogen or lower alkyl containing 1 to 6 carbon atoms; R' represents lower alkyl containing 1 to 6 carbon atoms, vinyl or ethynyl; R'' represents cycloalkyl containing 3 to 5 carbon atoms; and the wavy line represents optional R,S stereochemistry. These compounds are potent antisecretory compounds and cytoprotective agents with reduced diarrhea side effects. |
申请公布号 |
DE3475785(D1) |
申请公布日期 |
1989.02.02 |
申请号 |
DE19843475785 |
申请日期 |
1984.11.13 |
申请人 |
G.D. SEARLE & CO. |
发明人 |
COLLINS, PAUL WADDELL;GASIECKI, ALAN FRANK |
分类号 |
A61K31/557;A61K31/5575;A61P1/04;A61P43/00;C07C67/00;C07C401/00;C07C405/00;(IPC1-7):C07C177/00 |
主分类号 |
A61K31/557 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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