发明名称 Förfarande för framställning av farmakologiskt aktiva estrar och tioestrar
摘要 <p>Aromatic esters and thioesters have the formula <IMAGE> (I) wherein X represents oxygen or sulfur, R1 represents -CH2OH, -CH(OH)-CH3, -COOR5 or <IMAGE> R5 represents hydrogen, lower alkyl, lower alkenyl, monohydroxyalkyl or polyhydroxyalkyl, r' and r'' represent hydrogen, lower alkyl, monohydroxyalkyl, polyhydroxyalkyl, aryl or benzyl optionally substituted, the residue of an amino acid or aminated sugar, or taken together form a heterocycle, R2represents alpha , alpha '-disubstituted alkyl having 4-12 carbon atoms or mono- or polycyclic cycloalkyl having 5-12 carbon atoms whose carbon linking carbon is trisubstituted, R3represents hydrogen, lower alkyl, or -Si(CH3)2R'3 wherein R'3 represents lower alkyl, and R4 represents hydrogen or lower alkyl, and the salts of these aromatic esters and thioesters of formula (I) when R5 represents hydrogen. These aromatic esters and thioesters can be used in human and veterinary medicine and in cosmetic formulations.</p>
申请公布号 FI890291(A0) 申请公布日期 1989.01.19
申请号 FI19890000291 申请日期 1989.01.19
申请人 CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES 发明人 SHROOT, BRAHAM;EUSTACHE, JACQUES;BERNARDON, JEAN-MICHEL
分类号 A61K31/235;A61K8/00;A61K8/30;A61K8/37;A61K8/40;A61K8/41;A61K8/42;A61K8/44;A61K8/46;A61K8/49;A61K8/58;A61K31/265;A61K31/40;A61K31/445;A61K31/495;A61K31/535;A61K31/5375;A61P11/00;A61P17/00;A61P29/00;A61P35/00;A61P37/08;A61Q5/00;A61Q17/04;C07C67/14;C07C69/00;C07C69/92;C07C235/44;C07C327/32;C07D295/18;C07F7/18;(IPC1-7):C07C/ 主分类号 A61K31/235
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