| 摘要 |
<p>The isolation and purification of cytochalasins from mold culture, specifically purification of cytochalasins A and B from Drechslera dematioidea and of cytochalasin D from mold cultures of Zygosporium masonii is achieved by a method employing the step of extracting the mold matte producing the desired compound by a batch adsorption technique. Cytochalasins may be used in in vivo chemotherapy of invasive and metastatic disease, and in combination chemotherapy against neoplasms. Vehicles such as liposomes, which afford sustained release of the cytochalasin, may be used in the administration of such compounds.</p> |
