发明名称 DENTIFRICE CONTAINING DUAL SOURCES OF FLUORIDE
摘要 <p>Dentifrice comprising a liquid vehicle containing water, a gelling agent, a dual source of at least about 500 ppm of fluorine comprising sodium fluoride and sodium monofluorophosphate, a precipitated, amorphous silica gel having an average particle size of 1 to 30 microns and a) a surface area of 1 to 600 m2/g, b) a pore volume of 0.05 to 0.5 cm3/g, c) a product of surface area (in m2/g) x pore volume in cm3/g) less than or equal to 240, d) a calculated pore diameter of 1.5 to 2.5 nm, and e) a water content of less than 25% by weight, a source of calcium corresponding to up to about 0.004% by weight (40 ppm) of calcium ion and about 0.25%-5% by weight of an alkali metal phytate. The alkali metal phytate improves retention of total soluble fluorine, the dentifrice being stable in an unlined aluminium tube.</p>
申请公布号 CA1247531(A) 申请公布日期 1988.12.27
申请号 CA19850473231 申请日期 1985.01.31
申请人 COLGATE-PALMOLIVE COMPANY 发明人 MORTON, ANTHONY J.;HARVEY, KENNETH;HAYES, HARRY
分类号 A61K8/21;A61K8/24;A61K8/25;A61Q11/00;(IPC1-7):A61K7/18 主分类号 A61K8/21
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