| 摘要 |
PURPOSE:To enable the separation and purification of chlorotoluene preventing the corrosion of a distillation column caused by the formation of hydrogen chloride, by distilling a nucleus-chlorination reaction mixture of toluene in the presence of DMSO, thereby suppressing the decomposition and polymerization of a side-chain chlorination product. CONSTITUTION:A reaction mixture produced by the nucleus-chlorination of toluene and containing a slight amount of side-chain chlorinated by-product is added with 0.0001-1wt.% of DMSO and distilled according to conventional distillation process to effect the separation and purification of monochlorotoluenes such as o- or p-isomer and various kinds of dichlorotoluenes without causing the corrosion of the distillation column made of iron, nickel, etc., nor lowering the distillation efficiency caused by the decomposition of the side-chain chlorinated product and the deposition of polymers. The obtained chlorotoluene is useful as a production intermediate for pharmaceuticals and agricultural chemicals.
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