| 摘要 |
<p>Somatostatin peptides containing at least one residue of formula (a), (b) or (c> <IMAGE> wherein one of Y1 and Y2 is hydrogen and the other is hydroxy or both are hydrogen, each of f and g independently is 0 or 1, one of X1 and X2 is hydrogen and the other is hydrogen or an amino protecting group, and X3 is C2-4 alkylene, the free bond in each residue (a), (b) or (c) being located at the N-terminal group of the peptide, and the physiologically-acceptable ethers and physiologically-hydrolysable and -acceptable esters thereof when the peptide contains at least one residue of formula (a) or (b). In free form, salt form or complex form have pharmacological activity, in particular GH-, gastric and pancreatic secretion inhibiting activity.</p> |
