发明名称 |
External pharmaceutical composition and methods of use |
摘要 |
A pharmaceutical composition for external use with the enhanced penetration of a pharmacologically active agent through the skin or mucosa of a warm-blooded animal, said composition comprising (A) a pharmaceutically effective amount of the pharmacologically active agent, and (B) an optically active or inactive pyroglutamate of the following formula <IMAGE> (1) wherein R represents a linear, branched or cyclic alkyl or alkenyl group having 10 to 14 carbon atoms, as a penentration enhancer.
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申请公布号 |
US4789667(A) |
申请公布日期 |
1988.12.06 |
申请号 |
US19850771764 |
申请日期 |
1985.09.03 |
申请人 |
TEIJIN LIMITED |
发明人 |
MAKINO, YUJI;MATUGI, HIDEO;SUZUKI, YOSHIKI |
分类号 |
A61K47/22;(IPC1-7):A61K31/40;A61K31/56;A61K31/60;A61K31/62 |
主分类号 |
A61K47/22 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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