| 发明名称 |
5-substituted-2',3'-dideoxycytidine compounds with anti-HTLV-III activity |
| 摘要 |
5-substituted 2',3'-dideoxycytidine compounds and their monophosphates are disclosed which have been found to have potent activity against retroviruses. The 5-fluoro-and 5-aza-substituted 2',3'-dideoycytidine compounds have been found to be effective against HTLV-III/LAV virus.
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| 申请公布号 |
US4788181(A) |
申请公布日期 |
1988.11.29 |
| 申请号 |
US19860913575 |
申请日期 |
1986.09.29 |
| 申请人 |
THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF HEALTH AND HUMAN SERVICES |
发明人 |
DRISCOLL, JOHN S.;MARQUEZ, VICTOR E.;KIM, CHONG-HO;KELLEY, JAMES A. |
| 分类号 |
C07D405/04;(IPC1-7):A61K31/70;C07H19/06;C07H19/10 |
主分类号 |
C07D405/04 |
| 代理机构 |
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