| 摘要 |
NEW MATERIAL:A compound of the formula [W, X form >W-X such as carbonyl or beta-hydroxyl; Y, Z form -Y-Z such as -PPSe)CH-CH2-(PP is phenyl, 2-pyridyl), -CH=CH-, -CBr=CH-, OR<1>, OR<2> are acyloxy, sulfate ester or phosphate ester]. USE:A synthetic intermediate of 6alpha,9alpha-difluorocorticoids. PREPARATION:Pyridyl selenenyl chloride, pyridyl selenenyl bromide, phenyl selenenyl chloride or phenyl selenenyl bromide is allowed to act on 6beta,9alpha- difluoro-5alpha,17alpha,21-trihydroxypregna-3, 11, 2-trione-17,21-diester of 6beta,9alpha-difluoro-5alpha, 11beta,17alpha,21-tetrahydroxypregna-3,20-d-ione-17,21-diester.
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