发明名称 PHENYLPIPERAZINE DERIVATIVES AND PROCESS FOR PRODUCING THE SAME
摘要 <p>NOVEL PHENYLPIPERAZINE DERIVATIVES AND PROCESS FOR PRODUCING THE SAME Compounds of the formula (wherein R1 is a lower alkyl group, R2, R3 and R4, which may be the same or different, represent a hydrogen atom, a halogen atom, a lower alkyl group, a lower alkoxy group, a hydroxyl group, a trifluoromethyl group or a lower alkoxycarbonyl group; two adjacent-groups of R2, R3 and R4 may combine to form a methylenedioxy group; n is an integer of 2 to 6) or salts thereof, are disclosed. These compounds are useful as agents for treating circulatory diseases because they have hypotensive action and are capable of increasing the cerebral blood flow, decreasing the heart rate and suppressing ventricular arrhythmia due to myocardial ischemia.</p>
申请公布号 CA1244431(A) 申请公布日期 1988.11.08
申请号 CA19830436782 申请日期 1983.09.15
申请人 CHUGAI SEIYAKU KABUSHIKI KAISHA 发明人 NAGANO, HIROYUKI;TAKAGI, MITIRO;KUBODERA, NOBORU;MATSUNAGA, ISAO;NABATA, HIROYUKI;OHBA, YASUHIRO;SAKAI, KAZUSHIGE;HATA, SHUN-ICHI;UCHIDA, YASUMI
分类号 C07D295/12;A61K31/495;A61P9/00;A61P9/06;A61P9/10;A61P9/12;C07D295/13;C07D317/68;(IPC1-7):C07D295/14;C07D405/12 主分类号 C07D295/12
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