This invention relates to immunotherapeutic methods and compositions. More particularly, this invention relates to methods for eliciting specific antibody responses in immunodeficient patients using immunogens comprising antigen/T-cell independent carrier conjugates. According to a preferred embodiment, this invention relates to immunogens comprising peptides from the env region of the HIV genome coupled to T-cell independent carriers, which are useful in preventing or treating acquired immune deficiency syndrome and AIDS related complex.
申请公布号
WO8808429(A1)
申请公布日期
1988.11.03
申请号
WO1988US01213
申请日期
1988.04.20
申请人
BIOGEN N.V.;FISHER, RICHARD, A.
发明人
FISHER, RICHARD, A.;GILBERT, WALTER;SATO, VICKI, L.;RAMACHANDRAN, KUZHALMANNAM, L.