Method of manufacturing cis-2,6-dimethylmorpholine

摘要

Cis-2,6-dimethylmorpholine is manufactured by catalytic isomerization of trans-2,6-dimethylmorpholine. A previously hydrogen-activated copper chromite catalyst is used for catalytic isomerization of the trans-2,6-dimethylmorpholine. The catalyst preferably also contains barium oxide and/or manganese dioxide. The process is carried out at 180 DEG -300 DEG C. and 1-500 bar absolute. The inexpensive novel catalyst enables conversions which are better than those with known methods.