摘要 |
<p>2,4-Diaminopteridine derivatives and the pharmaceutically acceptable salts thereof having potent anticancer activity are disclosed. Said derivatives possess the structural formula: wherein Y is NH2, OH or SH, R is and X is in which R' is H or CH3 or in which R and R' are as previously defined, provided, when Y is NH2, R' must be CH3 and when Y is OH, R' must be H.</p> |