| 发明名称 |
Antiarrythmic agents. |
| 摘要 |
<p>Compounds of the formula:- <CHEM> and their salts, where R is -NHSO2(C1-C4 alkyl), -NH2 or -NO2; R<1> is C1-C4 alkyl; and "Het" is a group of the formula:- <CHEM> where R<2> is H, CH3 or C2H5; R<3> is -NHSO2(C1-C4 alkyl), -NH2 or -NO2; and X is O, S or NR<4> where R<4> is H or CH3; with the proviso that when one of R and R<3> is -NO2, then the other is not -NH2. The compounds of the formula (A) in which both R and R<3> are -NHSO2(C1-C4 alkyl) are antiarrhythmic agents. The reamining compounds of the formula (A) are synthetic intermediates.</p> |
| 申请公布号 |
EP0281254(A1) |
申请公布日期 |
1988.09.07 |
| 申请号 |
EP19880300962 |
申请日期 |
1988.02.05 |
| 申请人 |
PFIZER LIMITED |
发明人 |
CROSS, PETER EDWARD, DR.;THOMAS, GEOFFREY NOEL, DR.;ARROWSMITH, JOHN EDMUND, DR.;DICKINSON, ROGER PETER, DR. |
| 分类号 |
C07D209/14;A61K31/34;A61K31/343;A61K31/38;A61K31/381;A61K31/40;A61K31/403;A61K31/404;A61K31/42;A61K31/423;A61K31/425;A61K31/428;A61K31/47;A61P9/06;C07D215/12;C07D215/38;C07D235/06;C07D263/56;C07D277/64;C07D307/81;C07D333/58;(IPC1-7):C07D307/81;A61K31/635 |
主分类号 |
C07D209/14 |
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