发明名称 MEDICAMENT AND MEDICINAL COMPOSITION FOR THE TREATMENT OF INFECTIOUS DISEASES DUE TO VIRUSES,AS WELL AS FOR THE TREATMENT OF TUMORS
摘要 Said medicament is the L-glutamic acid gamma monohydroxamate (GAH). It inhibits totally viral multiplication (it is believed to belong to the category of inducers of the antiviral cellular state), and it shows a cytotoxic activity on different lines of human tumors (both solid tumors and lymphomas), the selectivity of action (cytolytic and irreversible on tumoral cells, and cytostatic reversible on normal cells) giving grounds to think that it uses a metabolic difference between tumoral cells and normal cells. The corresponding medicinal composition is in the form of a lyophilized powder, comprised of the active principle (GAH), to be dissolved extemporaneously in a physiological solution with a view to injection.
申请公布号 WO8707836(A3) 申请公布日期 1988.08.11
申请号 WO1987FR00230 申请日期 1987.06.18
申请人 VILA, JORGE;THOMASSET, NICOLE;EPSTEIN, ALBERTO;WILD, FABIAN;INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) 发明人 VILA, JORGE;THOMASSET, NICOLE;EPSTEIN, ALBERTO;WILD, FABIAN
分类号 A61K31/195 主分类号 A61K31/195
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