摘要 |
Four peptides have been isolated from mammalian atria which exhibit potent diuretic, natiuretic and vasodilatory properties. These peptides derive from a common precursor preprocardionatrin of 152 amino acids in a determined sequence. Cardionatrin III and IV, having molecular weights of about 8,000 and 13,700 respectively have been isolated, purified by chromatographic techniques and their amino acid sequence determined.
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