| 摘要 |
<p>A process for producing an alpha -(benzylidene)acetonylphosphonate of the formula: <CHEM> wherein Ar is phenyl substituted by at least one substituent selected from the group consisting of fluorine, chlorine, bromine, nitro, chloromethyl, dichloromethyl, trichloromethyl, trifluoromethyl, -CO2R<7> wherein R<7> is C1-C5 alkyl, -CONR<7>R<8> wherein R<7> is as defined above and R<8> is C1-C5 alkyl, -C(O)R<7> wherein R<7> is as defined above, -OC(O)R<7> wherein R<7> is as defined above, -OSO3R<7> wherein R<7> is as defined above, -OCF3, -S(=O)2R<7> wherein R<7> is as defined above, -CN and -SO3R<7> wherein R<7> is as defined above, and each of R<1> and R<2> which may be the same or different is a saturated or unsaturated C1-C12 aliphatic group, or R<1> and R<2> together form 1,2-ethylene, 1,3-propylene or 1,4-butylene, which is unsubstituted or substituted by from one to four C1-C3 alkyl groups, which comprises: (a) reacting an aldehyde of the formula: ArCHO (I) wherein Ar is as defined above, with an acetonylphosphonate of the formula: <CHEM> wherein R<1> and R<2> are as defined above, in the presence of secondary amine of the formula: <CHEM> wherein each of R<3> and R<4> which may be the same or different is C1-C4 alkyl, or R3 and R4 together form 1,4-butylene or 1,5-pentylene, which is unsubstituted or substituted by from one to four C1-C2 alkyl groups, -CH2CH2OCH2CH2- or -CH2CH2NHCH2CH2-, and an alpha -halogeno fatty acid of the formula: <CHEM> wherein X is fluorine, chlorine, bromine or iodine, and each of R<5> and R<6> which may be the same or different is hydrogen, fluorine, chlorine, bromine, iodine or C1-C4 alkyl; or (b) reacting a compound of the formula: <CHEM> wherein Ar, R<1> and R<2> are as defined above, with an acetonylphosphonate of the formula II as defined above, in the presence of an alpha -halogeno fatty acid of the formula V as defined above. c</p> |
