发明名称 DERIVATIVES OF DIHYDROPYRIDINE-3,5-DICARBOXYLATE AND PYRAN-3,5-DICARBOXYLATE
摘要 <p>Abtract New compounds, processes for their preparation and their use as medicanments Compounds of the formula < IMG > in which R is an optionally substituted aryl or heterocyclic radical, R1 is a hydrocarbon radical which is optionally interrupted by 1 oxygen atom in the chain, and/or which is optionally substituted, R4 is an aliphatic hydrocarbon radical having 7 to 14 carbon atoms, which is optionally interrupted by one oxygen atom and/or which is optionally substituted, R2 and R3 each independently is hydrogen, an alkyl radical, an aryl radical or an aralkyl radical, or, for the case where one of the substituents R2 or R3 has the above-mentioned meaning, the other is hydroxymethyl, acetoxymethyl or amino, and X is N-R5, wherein R5 is hydrogen, an alkyl radical which is optionally interrupted by an oxygen atom, a morpholinoalkyl radical, an aryl radical or an aralkyl radical or X is an oxygen atom, when one of the radicals R2 or R3 denotes an amino group, or pharmaceutically acceptable acid addition salts thereof, exhibit hypotensive activity.</p>
申请公布号 CA1239401(A) 申请公布日期 1988.07.19
申请号 CA19830423079 申请日期 1983.03.08
申请人 BAYER AKTIENGESELLSCHAFT 发明人 WEHINGER, EGBERT;MEYER, HORST;KNORR, ANDREAS
分类号 A61K31/455;A61P1/00;A61P9/06;A61P9/08;A61P9/10;A61P9/12;A61P11/00;A61P13/02;A61P15/00;A61P25/28;C07D211/90;C07D309/32;(IPC1-7):C07D211/90;C07D401/04 主分类号 A61K31/455
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