| 摘要 |
A continuous industrial separation process for biopolymer extracts each individual single component from a stream of cell extract. The process can be set up as a mixed flow reactor or fluidized bed in a continuous operation under normal pressure to treat a volume of cell extract in a short period of time. The separated single biopolymer is continuously withdrawn from the process and be easily condensed into the desired concentration. A resin, which can be an ion exchanger or affinity adsorbent or dye ligand adsorbent or hydrophobic adsorbent or immunoadsorbent, is evenly suspended in a well mixed reactor to equilibrate with the biopolymers in the liquid phase. The fundamental separation scheme is successive adsorption and desorption of biopolymer from liquid. Biopolymers are isolated into a single stream or multistreams for one component or many individual components. Each stream contains only one high purity biopolymer. The new process has the advantages of short operation time and economical usage of resin and high production throughput for treating massive volumes of cell extract in a continuous mode.
|
