| 发明名称 |
Mitotic kinesin inhibitors |
| 摘要 |
The present invention relates to cycloalkylpyrimidinone compounds that are useful for treating cellular proliferative diseases, for treating disorders associated with KSP kinesin activity, and for inhibiting KSP kinesin. The invention also related to compositions which comprise these compounds, and methods of using them to treat cancer in mammals.
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| 申请公布号 |
US2005107404(A1) |
申请公布日期 |
2005.05.19 |
| 申请号 |
US20040497413 |
申请日期 |
2004.06.02 |
| 申请人 |
FRALEY MARK E.;GARBACCIO ROBERT M. |
发明人 |
FRALEY MARK E.;GARBACCIO ROBERT M. |
| 分类号 |
A61K31/138;A61K31/395;A61K31/4465;A61K31/4535;A61K31/517;A61K31/519;A61K31/5377;A61K31/541;A61K31/5513;A61K39/395;A61K45/00;A61P35/00;A61P43/00;C07D239/70;C07D401/06;C07D401/12;C07D401/14;C07D403/06;C07D403/14;C07D413/14;C07D417/14;C07D487/10;(IPC1-7):A61K31/517;C07D43/02 |
主分类号 |
A61K31/138 |
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