| 摘要 |
Compounds of general formula I: <CHEM> wherein: X represents oxygen or sulphur; R<1> represents loweralkyl; R<2> represents hydrogen, halo, 4,5-benzo, loweralkoxy, amino, methylamino or dimethylamino; R<3> represents hydrogen or loweralkyl; and n is 1 or 2 and their pharmaceutically acceptable acid addition salts have anxiolytic activity. In particular, they have activity against anxiety induced by the withdrawal from ingested substances such as narcotics (eg cocaine), alcohol and nicotine. |
